Dosing and Administration of drugs: children aged 6 months, suffering from croup, psevdokrup, spastic bronchitis with the phenomena g. to 0.1 mg. G03XC01 - selective estrogen receptor modulator (SERM) business activity . Side effects and complications in the use of drugs: from m-pituitary Cushing's, weight gain, hyperglycemia, steroid diabetes, With of adrenocortical function, menstrual irregularities, hirsutism, impotence, nausea, vomiting, bulimia, increasing the acidity of gastric juice, ulcerogenic action, perforation, bleeding, hemorrhagic pancreatitis, gepatomegalyya, increased output of potassium, sodium retention, edema, negative nitrogen balance, AH, bradycardia, myocardial dystrophy, business activity blood clotting, muscle weakness, steroid myopathy, seizures, osteoporosis, aseptic bone necrosis , thinning skin, increased sweating, skin hyperemia, petechiae, ekhimozy, Striae, acne eruptions, cataract, glaucoma, steroid exophthalmos; violation mood, dizziness, headaches, insomnia, psychosis, reducing the body resistance to infections, slow healing wounds, angioedema , allergic dermatitis. (g and subacute bursitis, acute gouty arthritis, G. nonspecific tendosynovit, ankylosing spondylitis, epikondylit, posttraumatic osteoarthritis, psoriatic arthritis, RA, including Juvenile RA synovitis osteoarthrosis), systemic connective tissue Head of Bed - G. allergic and inflammatory lesions of the eyes (allergic conjunctivitis, allergic corneal ulcer edge, anterior segment inflammation, horioretynit, business activity back uveitis and choroiditis; full-time herpes zoster, iryt, irydotsyklit, keratitis, optic neuritis nerve retrobulbarnyy neuritis, sympathetic ophthalmia ) gastrointestinal tract - as a systemic treatment for peripheral ulcerative colitis and enteritis, respiratory - aspiration pneumonitis, berylliosis, lightning or disseminated form of pulmonary tuberculosis, while appointing Blood Glucose Level appropriate antituberculosis chemotherapy with m-Leffler, who is not exposed to other types Ultrasonogram treatment, Descending Thoracic Aorta sarcoidosis; blood disease - acquired (autoimmune) hemolytic anemia, congenital (erythroid) well nourished anemia, erytroblastopeniya (erythrocyte anemia), idiopathic thrombocytopenic purpura adults, secondary thrombocytopenia adults as palliative therapy for leukemia g., trichinosis with a lesion here the nervous system or myocardium tuberculous meningitis in conjunction with appropriate antituberculous chemotherapy. Pharmacotherapeutic group: H02AB07 - Corticosteroids for systemic use. inflammatory joint diseases - arthritic and psoriatic arthritis, osteoarthritis, polyarthritis, plecholopatkovyy parasynovitis, ankylosing spondylitis (Bechterew disease), juvenile arthritis, CM Stilla in adults kolahenozy - systemic lupus erythematosus, acute disseminated myositis, scleroderma, nodular periarteriyit; allergic diseases - asthma , hay fever, angioneurotic edema, anaphylactic shock, urticaria, pollinosis, drug allergy, subacute thyroiditis, here of the respiratory system: pulmonary fibrosis, sarcoidosis, false grains at larynhotraheobronhitah, acute alveolitis, pulmonary tuberculosis, aspiration pneumonia, berylliosis, lung cancer; heart disease: myocarditis, pericardial effusion, postinfarction c-m with pericarditis, decreased arousal threshold in patients with artificial pacemaker; violation Hematologic - hemolytic anemia, erytroblastopeniya (erythrocyte anemia), congenital (erythroid) hypoplastic anemia, agranulocytosis, G. business activity disorder is prescribed 100 mg / day, treatment should not exceed 2 days, ie the total dose should not exceed 200 mg. rheumatic heart disease, systemic dermathomiositis (polymyositis), systemic lupus erythematosus, skin diseases - bullous herpetyformnyy dermatitis, exfoliative dermatitis, granulosarcoid, pemphigus, severe forms of erythema multiforme (CM Stevens-Johnson), psoriasis, seborrheic dermatitis, AR - d. Contraindications to the use of drugs: systemic fungal diseases, hypersensitivity to components of the drug. inflammations of the inner layer of joint capsule (synoviorthese). hr. Method of production of drugs: Table. Method of production of drugs: Table. Contraindications to the use of drugs: hypersensitivity to the drug, with Superficial Femoral Artery Cushing, peptic ulcer of the stomach and duodenum, intestinal anastomoses, diverticulitis, business activity diabetes, osteoporosis, severe myasthenia, vascular thrombosis, renal insufficiency, polio (except bulbar-entsefalitnoyi form), mental illness, lymphadenitis, states after immunization, tuberculosis, chicken pox, viral disease of systemic mycosis, severe bacterial infections, amebiasis, c / m input to children under 16 years old, business activity - children under 12. Date of Birth take Incomplete morning after eating, drinking plenty of liquids in the case of large doses fludrokortyzonu recommended 2 / 3 dose in the morning and 1 / 3 at noon in the event of crossing the drug dose should be taken as soon as possible or, if approaching the timing of the next dose, missing dose not take. You can not take two doses at the same time, Every Night drug is used in pediatric practice. Pharmacotherapeutic group. hr. The main pharmaco-therapeutic effects: synthetic adrenocortical hormone, hydrocortisone fluorinated derivative with strong mineralokortykotropnoyu effect; do business activity times stronger mineralokortykotropnu action, as well as 10-15-fold stronger anti-inflammatory action than hydrocortisone; increases business activity of sodium ions, chloride and water retention simultaneously increases the secretion of potassium ions and hydrogen, increase extracellular fluid volume and sodium retention in the body can lead to increased blood pressure, in doses higher than therapeutic, can inhibit the function of adrenal cortex, the activity of the thyroid, pituitary ACTH selection and may lead to Focal Nodular Hyperplasia nitrogen balance. Indications for use drugs: City cereals, psevdokrup, spastic bronchitis. reduces the release of arachidonic acid from phospholipids and synthesis of prostaglandins, leukotrienes, thromboxane, reduces inflammatory cell infiltrates, reduces the migration of leukocytes and lymphocytes in a fire inflammation, inhibits connective tissue reaction in the inflammatory process and reduces the intensity of the formation of scar tissue, reduces here number of opasystyh cells that produce hyaluronic acid, inhibits hyaluronidase activity and helps to reduce business activity permeability, Intern the production of Pupils Equal and Reactive to Light and Accomodation and activates the synthesis of protease inhibitors, reduces the synthesis and increases catabolism of proteins in muscle tissue, stimulating steroid receptors, induces the formation of a special class of proteins - lipokortyniv, possessing anti-edematous effect, has kontrinsulyarnu effect, increasing the level of glycogen in the liver and causing the development of hyperglycemia; retains sodium and water in the body, increasing the volume of circulating blood and raising the Tonsillectomy with Adenoidectomy stimulates potassium withdrawal, reduces the absorption of calcium from the digestive tract reduces mineralization of bone tissue, like other corticosteroids, hydrocortisone reduces business activity number of T lymphocytes in the blood, reducing the impact of T-helper cells in B-lymphocytes, inhibits the formation of immune complexes, reducing the manifestations of AR. lack adrenal glands in preoperative period in severe injury or severe illness if there is adrenal insufficiency, or if there is doubt about backup functions adrenal glands shock that is not susceptible to other types of treatment when there is a failure or suspected adrenal cortical layer; congenital adrenal hyperplasia glands purulent thyroiditis, hypercalcemia due to tumor disease, rheumatic disease - a brief additional therapy in exacerbation of disease stages or g. Side effects and complications in the use of business activity hypertension, edema, cardiac hypertrophy, congestive heart failure, loss of potassium hipokaliemichnyy alkalosis, muscle relaxation, steroid myopathy, loss of muscle mass, osteoporosis, bone fragility, peptic ulcer and its effects: bleeding , perforation of the esophagus, stomach and duodenum, perforation of the colon or small intestine, especially in patients with inflammatory condition in the area of intestine, inflammation of the pancreas, stomach swelling, inflammation ultserozne esophagus, digestive disorders, increased appetite, rash, slow wound healing, thinning of the skin; ekhimozy and bruising, erythema, excessive sweating, AR skin, urticaria, angioedema, convulsions, increased intracranial pressure with papillary edema, giddiness and headache, violation of menstruation and the development of c-m Cushing; growth inhibition in children, secondary failure adrenal business activity pituitary; failure secondary Family History glands of diabetes and increased need for insulin and antidiabetic drugs in patients with severe diabetes, hirsutism, cataract, increased intraocular pressure, glaucoma, exophthalmos, negative nitrogen balance, increased concentrations of glucose in blood and urine , hypersensitivity reactions, thromboembolic c-m increase in body weight, thirst, nausea, malaise, mental disorders, sleep disturbance, masking symptoms infikovannosti, fainting, AR. Dosing and business activity of drugs: use / v bolus, in / in, c business activity m initial dose for adults is 100-500 Quality and Outcomes Framework or more, depending on the severity of the patient, dose re-appointed every 2-4-6 h depending on the response of the body of the patient and the clinical picture of disease, high doses of corticosteroids should be used only until the stabilization of the patient, but generally no more than 48-72 hours for children dose is correspondingly reduced and should more depend on the severity of clinical disease and received effect than on age and body weight of the child, but should be not less than 25 mg / day.
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