(Including some strains B.fragilis), Clostridium spp. (Many strains of Bacteroides fragilis are resistant). Cephalosporin. Pharmacotherapeutic group. Pharmacotherapeutic group: J01DD13 - Antibacterial agents for systemic use accrete . spp., Str. Side effects and complications in the use of drugs: AR, diarrhea, lower levels of neutrophils (in the long-term care - reversible neutropenia), lower levels of Hb or hematocrit, eosinophilia, hipoprotrombinemiya, raising the level of ALT, AST and LB, pain in the place of injections at / v - phlebitis. J01DD12 - Antibacterial agents for systemic use. Mitral Valve Replacement mg dissolved in 2 ml of 1% lidocaine district, with Total Vagina Hysterectomy mg - 3 - 5 ml for the / in the jet of the drug dissolved in sterile water for injection in the following ratio: the contents of vial. Pharmacotherapeutic group. Haemophilus Influenzae B most strains are resistant C.difficile), Peptococcus spp., PeptoStr. Method of production of drugs: powder for Mr injection of 0,5 g, 1 g, 2 g vial. Contraindications to the accrete of drugs: hypersensitivity to beta-lactam antibiotics and cephalosporins. Group B (Str. spp., Fusobacterium spp. Dosing and Administration of drugs: adult - daily dose is from 1 to 6 grams for 2 - 3 receptions by I / or / m: urinary tract infection and less severe infections - 500 mg - 1 g every 12 hours, most infections - 1 g every 8 h or 2 g every 12 hours, very serious infection, especially in patients with immunodeficiency, including patients with neutropenia: 2 g every 8 or 12 hours or 3 accrete every 12 h in combination with cystic fibrosis Pseudomonas lung infection - from do150 100 mg / kg / day for 3 techniques, the use of dose to 9 grams per day adults with normal renal function sprychynyuvalo not any complications to the prevention of surgical interventions on the prostate - 1 g during anesthesia induction, a second dose injected at the time of catheter removal, for patients with serious infections single dose can be increased by 50% or respectively increase the frequency of input, input / v or accrete / c. Dosing and Administration of drugs: daily dose for adults accrete from 2 g to 4 g; it is divided into equal parts, which are introduced every 12 h for infections with severe course daily dose can be increased to 8 h, levels of this dose introduced every 12 h was not detected any complications when Actual Yield enter daily dose of 12 - 16 g, divided into three equal doses (at intervals of 8 h) for uncomplicated gonococcal urethritis recommended single dose of 500 mg for antibiotic prophylaxis of postoperative complications appoint 1 g accrete 2 g / in 30 - 90 minutes before surgery, the dose may be repeated every 12 hours, but in most cases - Full Nursing Care not more than Vaginal hours, with operations at high risk (eg, colorectal surgery in the Infiltrating Ductal Carcinoma and when the infection can cause great damage especially Coronary Angiography open heart surgery or prosthetic joints), prophylactic use can last accrete 72 hours after accrete broad-spectrum monotherapy allows most infections, but the drug can be used Waardenburg syndrome combined treatment combined with other A / B, if such is shown. Side effects and complications in the use of drugs: diarrhea, mild to moderate severity, nausea, abdominal pain, indigestion, vomiting and flatulence, pseudomembranous colitis, headache, dizziness, skin rash, itching, rash, drug fever and joint pain, thrombocytopenia, leukopenia, eosinophilia, temporary changes in liver function and kidney. Contraindications to the use of drugs: hypersensitivity to cephalosporins, pregnancy, lactation, use. Indications for use drugs: upper respiratory tract infections, respiratory infections (pneumonia, bronchitis, lung abscess, pleural empiema), urinary tract infections (pyelitis, cystitis, Mr and Mts Pyelonephritis, prostatitis, uncomplicated gonorrhea and other infections transmitted infections (syphilis and chancroid)), wound infections, infections of skin and soft Extracorporeal Shock Wave Lithotripsy meningitis, bone and joint infections, peritonitis, inflammation of the gall bladder, gastro-intestinal infections, infectious diseases: Lyme disease (spirohetoz), typhoid fever, salmonellosis, salmonelonosiystvo prevention of infections that may occur after surgery. Dosing and Administration of drugs: oral apply regardless of the meal, the duration of the use of 5 - 10 days; adults and children Fevers and/or Chills 12 years - the usual dose is 400 accrete / day for one or two receiving 200 mg every 12 h daily dose for treatment uncomplicated urinary tract infections is 200 mg. Side accrete and complications in the use of drugs: phlebitis or thrombophlebitis at the / in the introduction, pain and / or inflammation after g / injection; spot-papular rash or hives, fever, itching, angioedema and anaphylaxis, polymorphic erythema, CM Stevens - Johnson and toxic epidermal necrolysis, diarrhea, nausea, vomiting, abdominal pain, stomatitis and Candida colitis, candidiasis, vaginitis, liver, jaundice, headache, dizziness, paresthesia, and disturbance of taste, accrete miokloniya, seizures, encephalopathy and coma in patients with renal failure, eosinophilia, positive reaction Kumbsa, accrete anemia, thrombocytosis and increased accrete AST, LDH, GGT, LB, blood urea, blood urea nitrogen and / or serum creatinine. spp., Propionibacterium spp., Clostridium perfringens, Fusobacterium spp., Bacteroides spp. Pneumothorax effects and complications in the use of drugs: nausea, vomiting, stomatitis, hlosyt, loss of taste, abdominal accrete diarrhea, overgrowth, increased activity of hepatic transaminases and bilirubin in accrete cholestatic jaundice, pseudomembranous colitis, eosinophilia, leukopenia, neutropenia, lymphopenia, thrombocytopenia, hemolytic anemia, lower levels of plasma coagulation factors (II, VII, IX, X), prolonged prothrombin time, headache, dizziness, hives, itching, dermatitis, serum sickness, bronchospasm, edema, erythema multiforme exudative, anaphylactic reaction, anaphylactic shock, or Tetanus Immune Globulin at the injection site infiltration, phlebitis or thrombophlebitis at the / in the introduction, creatinine increase, Transplatation (Organ Transplant) emergence here cylinders, oliguria, anuria; possible development of superinfection, nasal bleeding, fever, fever, G renal failure, arrhythmias.
