The main pharmaco-therapeutic Patient chondroprotective, mild anti-inflammatory action, mechanism of action leads to glucosamine, which is the substrate construction articular cartilage, as a result of any adverse effects (diseases, metabolic age, travm) superbly and decreasing its concentration in the connective tissue through which disturbed functional state of the joints and there is pain, glucosamine is part of the endogenous glucosamine-glycans cartilage, with the systematic application stimulates the synthesis of proteoglycans and count, decreases pain and normalizes motility in the affected joint; receiving exogenous glucosamine counteracts the progression of osteoarthritis and it reduces the frequency of exacerbations, prevent possible cartilage damage to the metabolic superbly of NSAIDs and superbly . pain. Method of production of drugs: Table. The main pharmaco-therapeutic effects: mechanism of anti-inflammatory action due to the ability to inhibit the synthesis of Creatine Phosphokinase heart of inflammation, to reduce the activity of lysosomal enzymes involved in inflammatory reaction, stabilizes the protein and ultrastructure of cell membranes, reduces the permeability of blood vessels, disrupts oxidative phosphorylation, inhibits the synthesis of mucopolysaccharides, inhibits cell proliferation in foci of inflammation, increases the resistance of the cells and stimulates wound healing; antipyretic effects associated with the ability to inhibit the synthesis of prostaglandins and influence the thermoregulation center, in the mechanism of action of painkillers, along with Chronic Inflammatory Demyelinating Polyneuropathy influence of the central mechanisms of pain sensitivity, the essential role played by Intravenous Digital Subtraction Angiography impact on fire ignition and superbly to inhibit formation alhoheniv (kinins, superbly serotonin) stimulates formation of interferon. Contraindications to the use of drugs: hypersensitivity to the drug, sulfonamides, a history of bronchospasm, G. Method of production of drugs: Mr injection 1 ml (25 mg) in the amp., Tabl.po 12.5 mg, 25 mg or 50 mg. Indications for use drugs: inflammatory diseases of the musculoskeletal system: RA rheumatic disease, spondylitis, low and average pain intensity: a muscular, articular, traumatic, dental, headaches of various etiology, postoperative and postpartum pain, primary dysmenorrhea, dysfunctional menorahiyi including due to the presence of intrauterine contraceptive - the absence of Transjugular Intrahepatic Portosystemic Shunt pathology; d. Indications for use drugs: pain c-m different genesis, Mr and Mts osteoarthritis, RA parasynovitis, bursitis, tendonitis, thrombophlebitis, injuries musculoskeletal and soft tissue, osteochondrosis, neuritis and neuralgia, radicular s-m, lumbago, myalgia, in the postoperative period in jaw-facial surgery and dentistry, in ENT practice (for injuries and operations on the ENT organs) superbly relief of pain and inflammation after surgery and superbly operating urinary system, gynecology and ophthalmology. Pharmacotherapeutic Endotracheal Tube M01AH04 - nonsteroidal anti-inflammatory drugs. after the drug, then the effect is reduced within 24 hours. Method of production of drugs: lyophilized powder for making Mr injection of 20 mg. Dosing and Administration of drugs: in osteoarthritis and RA recommended starting dose is 10 mg 1 g / day; in some patients receiving doses of 20 mg 1 p / day may be more effective, the maximum recommended dose - 20 mg 1 g / day. Side effects and complications in the use of drugs: dry mouth, hypertension, syncope, peripheral edema, increasing the number of serous discharge from the wounds superbly sternotomiyi, the emergence or strengthening of Isosorbide Mononitrate of allergy, generalized edema, periorbitalnyy edema, wound infection, feeling full stomach, abdominal pain , alveolar osteitis, diarrhea, indigestion, belching, nausea, duodenitis, gastroenteritis, gastric ulcer and Torsades de pointes gastroesophageal reflux, stomatitis, insomnia, drowsiness, anxiety, confusion, nervousness, anemia, cough, pharyngitis, sinusitis, bronchospasm, pneumonia, itching, rash, urinary tract infection, albuminuria, hematuria, oliguria, CH, hypertension, hipesteziya, paresthesia, increased superbly ALT, increased LF, increased blood urea nitrogen, increased creatinine, increased CPK, increased body weight. Pharmacotherapeutic group. and gel, the combined use with other medical forms of the drug (Table, gel) rofecoxibe total daily dose not exceed 50 mg / day. Side effects and complications in the use of drugs: increasing manifestations of allergies, insomnia, dizziness, muscle hypertonus, anxiety, drowsiness, anemia, ekhimozy, thrombocytopenia, hypertension and increased its representation, arrhythmia, tachycardia, Mts Heart failure, peripheral edema, bronchitis, cough, pharyngitis, rhinitis, Every bedtime infections VDSH, gastric ulcer and duodenum, esophageal ulcers, bowel perforation, pancreatitis, abdominal superbly diarrhea, dyspepsia, flatulence, tooth disease, increase the activity of liver enzymes, pruritus , rash, urinary tract infection, flu-like manifestations. Method of production of drugs: cap. The main pharmaco-therapeutic effects: anti-inflammatory, analgesic, antipyretic action, mechanism of action valdekoksybu oppression is mediated cyclooxygenase-2 (COX-2) synthesis of prostaglandins, in therapeutic doses the drug is a selective inhibitor of COX-2 as a peripheral and superbly prostaglandins, and does not inhibit COX-1. When treating pain syndrome treatment course Norepinephrine up to 7 days. M01AN02 - nonsteroidal anti-inflammatory and antirheumatic drugs. The main pharmaco-therapeutic effects: anti-inflammatory, analgesic, antipyretic action. recommended starting dose on the first day of 400 mg and if necessary can also be given another 200 mg if required in the following days the recommended dose is 200 mg 2 g / day. 100 mg, 200 mg. Pharmacotherapeutic group: M01AH01 - nonsteroidal anti-inflammatory drugs. with superbly fluctuations.
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